1. Validation and prediction of traditional Chinese physical operation on spinal disease using multiple deformation models.

Pan L, Yang X, Gu L, Lu W, Fang M.



School of Software, Shanghai Jiao Tong University, Shanghai, China.



Traditional Chinese medical massage is a physical manipulation that achieves satisfactory results on spinal diseases, according to its advocates. However, the method relies on an expert's experience. Accurate analysis and simulation of massage are essential for validation of traditional Chinese physical treatment. The objective of this study is to provide analysis and simulation that can reproducibly verify and predict treatment efficacy.


An improved physical multi-deformation model for simulating human cervical spine is proposed. First, the human spine, which includes muscle, vertebrae and inter- vertebral disks, are segmented and reconstructed from clinical CT and MR images. Homogeneous landmark registration is employed to align the spine models before and after the massage manipulation. Central line mass spring and contact FEM deformation models are used to individually evaluate spinal anatomy variations. The response of the human spine during the massage process is simulated based on specific clinical cases.


Ten sets of patient data, including muscle-force relationships, displacement of vertebrae, strain and stress distribution on inter-vertebral disks were collected, including the pre-operation, post-operation and the 3-month follow-up. The simulation results demonstrate that traditional Chinese massage could significantly affect and treat most mild spinal disease.


A new method that simulates a traditional Chinese medical massage operation on the human spine may be a useful tool to scientifically validate and predict treatment efficacy.

PMID: 20571927

[PubMed - in process]


2. Pain after spinal cord injury: a review of classification, treatment approaches, and treatment assessment.

Cardenas DD, Felix ER.




Department of Rehabilitation Medicine, University of Miami Miller School of Medicine, P.O. Box 016960 (C-206), Miami, FL 33010, USA. dcardenas@med.miami.edu


Pain is a prevalent consequence of spinal cord injury (SCI) that can persist for years after the injury and can have a significant impact on physical and emotional function and quality of life. There are a variety of types of pain that may develop after a SCI, including those of primarily nociceptive origin and those of primarily neuropathic origin. Recommendations for diagnostic and treatment strategies have been varied in part because of the lack of a universal classification system and in part because of the biopsychosocial nature of pain. The most recent taxonomy for pain after SCI is described herein. Pain-management strategies, including pharmacological, interventional, and psychological treatments, also are described. For neuropathic pain in SCI, anticonvulsant agents and tricyclic antidepressants often are tried, but these treatments have had limited success in many patients, and alternative interventions (eg, massage therapy, acupuncture, meditation) often are just as successful. Treatment of nociceptive pain after SCI often includes nonsteroidal antiinflammatory agents and acetaminophen, but correction of underlying etiologies and behavior adjustments also should be implemented if possible. An overview of self-report pain questionnaires and scales is also presented to provide the clinician and researcher with a set of tools to evaluate the efficacy of pain interventions.

PMID: 19797006

[PubMed - indexed for MEDLINE]


3. Complementary and alternative medicine use in Gilles de la Tourette syndrome.

Kompoliti K, Fan W, Leurgans S.




Department of Neurological Sciences, Section of Movement Disorders, Rush University Medical Center, 1725 W. Harrison street, suite #755, Chicago, Illinois 60612, USA. kkompoli@rush.edu


The aim of this study was to describe the use of complementary and alternative medicine (CAM) in patients with Tourette syndrome (TS) and explore associations with CAM use. In recent years CAM use has increased, but rates of CAM use in TS patients are not reported. Consecutive TS patients or their parent(s), seen in an academic movement disorder center, completed a questionnaire regarding their use of CAM. One hundred TS patients or parents completed the questionnaire, mean age 21.5 +/- 13.5, 76 males, 87 Caucasians. Sixty four patients had used at least one CAM modality. CAM treatments used were prayer (28), vitamins (21), massage (19), dietary supplements (15), chiropractic manipulations (12), meditation (10), diet alterations (nine), yoga (nine), acupuncture (eight), hypnosis (seven), homeopathy (six), and EEG biofeedback (six). Fifty six percent of patients using CAM reported some improvement. Users paid out of pocket for 47% of treatments pursued, and 19% of these payers received partial reimbursement by third party payer. Users and non-users did not differ in age, gender, race, income, educational level, general health, tic severity, medication use for TS, current satisfaction from medications or experience of side effects from medications. CAM use was associated with the presence of affective disorder (P = 0.004), but not with either ADHD or OCD. Among CAM users, 80% initiated CAM without informing their doctor. CAM is commonly used in children and adults with TS, and often without the neurologist's knowledge. Physicians should inquire about CAM to understand the spectrum of interventions that patients with TS use.

PMID: 19705358

[PubMed - indexed for MEDLINE]


4. Complementary and alternative medicines in ankylosing spondylitis: a cross-sectional study.

Chatfield SM, Dharmage SC, Boers A, Martin BJ, Buchanan RR, Maksymowych WP, Schachna L.




Department of Rheumatology, Royal Melbourne Hospital, Parkville, VIC, Australia.


Prevalence of dietary complementary and alternative medicine (CAM) and consultation with a CAM practitioner was examined in a cross-sectional study of 75 AS patients. Seventy one of 75 (94.7%) study participants reported previous or current CAM use. Among these AS patients, 44 (72.1%) reported dietary CAM use and 27 (36.0%) were seeing a CAM practitioner at the time of study. Of 89 dietary CAM, 50 (56.4%) were perceived to be of slight or no benefit, and only 10 (11.2%) were initiated by a CAM practitioner. Compared with non-users, current dietary CAM users were more likely to be female (OR 6.5; 95% CI, 1.8-23.9). Patients attending a CAM practitioner were more likely to have university education (OR 5.7; 95% CI, 1.5-21.9) and higher BASDAI (OR 1.3; 95%CI, 1.0-1.7). Despite low rates of perceived benefit, dietary CAM use and CAM practitioner attendance is common among AS patients.

PMID: 18985421

[PubMed - indexed for MEDLINE]


5. Symptom management and self-care for peripheral neuropathy in HIV/AIDS.

Nicholas PK, Kemppainen JK, Canaval GE, Corless IB, Sefcik EF, Nokes KM, Bain CA, Kirksey KM, Eller LS, Dole PJ, Hamilton MJ, Coleman CL, Holzemer WL, Reynolds NR, Portillo CJ, Bunch EH, Wantland DJ, Voss J, Phillips R, Tsai YF, Mendez MR, Lindgren TG, Davis SM, Gallagher DM.




Brigham and Women's Hospital, MGH Institute of Health Professions, Boston, MA, USA. pnicholas@mghihp.edu


Peripheral neuropathy is the most common neurological complication in HIV and is often associated with antiretroviral therapy. As part of a larger study on self-care for symptoms in HIV disease, this study analyzed the prevalence and characteristics of peripheral neuropathy in HIV disease, sociodemographic and disease-related correlates and self-care strategies. A convenience sample of 1,217 respondents was recruited from data collection sites in several US cities, Puerto Rico, Colombia and Taiwan. Results of the study indicated that respondents with peripheral neuropathy (n=450) identified 20 self-care behaviors including complementary therapies, use of medications, exercise and rest and/or elevation of extremities. Ratings of frequency and effectiveness were also included. An activities checklist summarized into five categories of self-care behaviors including activities/thoughts, exercise, medications, complementary therapies and substance was used to determine self-care behaviors. Taking a hot bath was the most frequent strategy used by those with peripheral neuropathy (n=292) and received the highest overall rating of effectiveness of any self-management strategies included in this study at 8.1 (scale 1-10). Other self-care strategies to manage this symptom included: staying off the feet (n=258), rubbing the feet with cream (n=177), elevating the feet (n=236), walking (n=262), prescribed anti-epileptic agent (n=80), prescribed analgesics (n=84), over-the-counter medications (n=123), vitamin B (n=122), calcium supplements (n=72), magnesium (n=48), massage (n=156), acupuncture (n=43), reflexology (n=23) and meditation (n=80). Several behaviors that are often deemed unhealthy were included among the strategies reported to alleviate peripheral neuropathy including use of marijuana (n=67), cigarette smoking (n=139), drinking alcohol (n=81) and street drugs (n=30).

PMID: 17364396

[PubMed - indexed for MEDLINE]


6. Treatments for chronic pain in persons with spinal cord injury: A survey study.

Cardenas DD, Jensen MP.




University of Washington, Department of Rehabilitation Medicine, Box 356490, Seattle, WA 98195, USA. dianamac@u.washington.edu



To determine the degree and duration of pain relief provided by specific pain treatments used by individuals with spinal cord injury (SCI) who have chronic pain.


Postal survey.




Participants were 117 individuals who had traumatic SCI, were 18 years of age or older, and reported a chronic pain problem.


Questions assessing current or past use of 26 different pain treatments, the amount of relief each treatment provided, and the length of time that any pain relief usually lasts.


The medications tried most often were nonsteroidal anti-inflammatory drugs (tried by 71%) and acetaminophen (tried by 70%); these medications were still being used by more than one half of the patients who had tried them. Opioids produced the greatest degree of pain relief on average (mean, 6.27 +/- 3.05 [SD] on a 0-10 scale, with 0 = no relief and 10 = complete relief) but were unlikely to be continued by those who tried them. Although 38% of respondents with pain had tried gabapentin, only 17% were still using it, and average pain relief was only moderate (mean, 3.32 +/- 3.03 on the 0-10 relief scale). Seventy-three percent of the respondents had tried at least 1 of 7 alternative pain treatments, and the most frequently tried were massage, marijuana, and acupuncture. The most relief was provided by massage (mean, 6.05 +/- 2.47] on the 0-10 relief scale) and marijuana (mean, 6.62 +/- 2.54 on the 0-10 relief scale). The relief from the various treatments, including most medications, tended to last only minutes or hours; however, pain relief from alternative treatments such as massage, acupuncture, and hypnosis was reported to last for days in 25% to 33% of those who tried these treatments.


Many patients are not finding adequate pain relief from commonly prescribed medications. Alternative therapies should be considered as additional treatment options in this population.

PMID: 16739554

[PubMed - indexed for MEDLINE]

PMCID: PMC1864800

Free PMC Article


7. Treatment of Bell's palsy with combination of traditional Chinese medicine and western medicine].

[Article in Chinese]

Wang XH, Zhang LM, Han M, Zhang KQ, Jiang JJ.




Rehabilitation Center of West China Hospital, Sichuan University, Chengdu 610041, China.



To evaluation the clinical effect of combination of traditional Chinese medicine and western medicine on Bell's palsy.


83 patients with Bell's palsy were randomly divided into two groups (trail group 54 cases and control group 29 cases). Patients in two groups were treated with medicine, acupuncture, physiotherapy, while patients in the trail group were treated with massage and functional exercise as the same time. The results of both groups were evaluated according to Portmann's Simple Scale.


The score before treatment of trail group was 2.907 +/- 1.794, while control group was 2.931 +/- 2.034. And the score after treatment of trail group was 18.593 +/- 1.743, while control group was 9.862 +/- 3.091. Score of the function of facial muscles obtained from trail group was distinctly higher than that was from the control group (P < 0.01), as well as the improvement index (P < 0.01, trail group: 0.844 +/- 0.095, control group: 0.712 +/- 0.129).


There is significant curative effect and suitability in the treatment of Bell's palsy with combination of traditional Chinese medicine and western medicine. The improvement of facial muscles' motive function pre- and post-treatment and quantitative evaluation of curative effect can be objectively obtained by evaluation of facial muscles' function.

PMID: 15293466

[PubMed - indexed for MEDLINE]

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